The Department of Health has confirmed that 381 new cases of COVID-19 have been reported in Ireland today.
The figures show that as of midnight on Friday, there were 110 people being treated in hospital for the virus.
Of these patients, 42 are in ICU.
The Department warned that daily case numbers may change due to future data validation following the HSE cyber attack.
Ministers met again today to review progress in our response to last week's cyber-attack on the HSE and to coordinate ongoing actions across Government.
Eamon Ryan, Stephen Donnelly, Heather Humphreys and Ossian Smyth, have been meeting daily to monitor and steer the Government's response.
They were updated on the "good" progress made with the restoration of HSE and hospital IT systems essential to the restoration of care for patients.
'Fraught with risk'
It comes as the CEO of the HSE has warned that the process of getting the health service's IT systems back up and running will be "fraught with risk" in the weeks ahead.
Paul Reid welcomed the news that the hackers behind last week's ransomware attack had handed over a decryption tool to unlock the stolen data.
However, he added that it would not be a matter of simply switching back on the systems.
The decryption code is being analysed this weekend to see if it can be safely used to regain access to patient data.
The criminal gang gave it to Irish authorities on Thursday, and the Government has said it has not paid a ransom to get the key.
Thousands of hospital appointments will be cancelled again next week, including outpatient consultations countrywide.
Our focus on protecting the public through vaccination remains unrelenting. Without the impacted data from GPs, we've likely well over 2.3M vaccines administered. Approx. 45% of adult population had a 1st Dose and over 15% fully vaccinated. A good lft for our teams too. @HSELive
— Paul Reid (@paulreiddublin) May 22, 2021
Meanwhile, the Minister for Health Stephen Donnelly has removed six countries from the list of designated states for mandatory hotel quarantine.
The countries are Andorra, Georgia, Kuwait, Mongolia, Nigeria and Puerto Rico.
All travellers into Ireland must have a negative pre-departure test and those from non-designated countries must observe home quarantine.