Leinster can go top of the Pro-12 table this evening with a bonus point win from their clash with Newport Gwent Dragons.
Zane Kirchner will make his first start for the Blues as they travel to Rodney Parade at 7.05pm.
Also tonight, Edinburgh host Zebre at Murrayfield from 7.45pm.
Meanwhile, Munster, Ulster and Connacht have all named their teams for tomorrow's matches.
Munster have made eight changes for their clash with the Ospreys at Thomond Park, with Donncha O'Callaghan starting in the second-row after being released from the Ireland camp.
Head coach Rob Penney has named a completely different front-row as Dave Kilcoyne and BJ Botha will partner team captain Damien Varley.
Ulster also make eight changes for tomorrow's visit to the Scarlets.
Andrew Trimble and Roger Wilson both start after spending the week with the Ireland squad.
Jared Payne takes on the captain's role and plays at full-back.
Connacht have made four changes for their game against the Glasgow Warriors at the Sportsground.
Dave McSharry makes his first start in ten months and will be joined in the centre by Darragh Leader.
Fionn Carr starts on the right wing while hooker Jason Harris-Wright has also been given a chance to impress.
Zane Kirchner ©INPHO/Donall Farmer