Real Madrid advanced to the Champions League semi-finals after a late goal from Javier 'Chicharito' Hernandez knocked out Atletico.
The Mexican striker was set up by Cristiano Ronaldo to score the only goal of the tie.
Atletico had Arda Turan sent off for a second yellow card as last year's finalists bowed out.
Advertisement
Meanwhile, Juventus also reached the last-four for the first time in 12 years after a 1-0 aggregate victory over Arsenal's conquerors Monaco.
The Italians won the first leg by a goal and played out a scoreless draw to qualify.