British Prime Minister Boris Johnson has suffered a double blow after his Conservative Party lost two by-elections.
This also prompted the Conservative Party chairman Oliver Dowden to quit.
The party saw a majority of 24,000 in the Devon constituency of Tiverton and Honiton evaporate - a record reverse for the party - as the Liberal Democrats swooped in.
While in the Yorkshire constituency of Wakefield, Labour took the seat.
Following the results, Mr Dowden resigned and said in a letter to Mr Johnson: "We cannot carry on with business as usual."
It was the latest electoral mauling for Mr Johnson this year, after the Tories lost nearly 500 council seats at the start of last month.
Simon Lightwood, who won the Wakefield by-election for Labour, said: "I think people are absolutely tired of the lies and deceit we've seen from the prime minister and they're demanding change and tonight is the demonstration of that."
Richard Foord, who took the Devon seat for the Lib Dems, used his acceptance speech to call for the British prime minister "to go, and go now", claiming his victory had "sent a shockwave through British politics".
Mr Johnson has been under pressure over the partygate scandal, as well as the cost of living crisis.
That pressure intensified when a no-confidence vote saw 148 Conservative MPs oppose him.
Labour leader Keir Starmer said: "Wakefield has shown the country has lost confidence in the Tories.
"This result is a clear judgement on a Conservative Party that has run out of energy and ideas."
Liberal Democrat leader Ed Davey said: "The Liberal Democrats have made political history with this stunning win.
"This should be a wake-up call for all those Conservative MPs propping up Boris Johnson. They cannot afford to ignore this result.
"The public is sick of Boris Johnson's lies and law-breaking and it's time for Conservative MPs to finally do the right thing and sack him."
The by-elections took place on the sixth anniversary of the country's Brexit referendum.
Reporting by: IRN