India has been added to a list of mandatory quarantine states by the Government, alongside four others.
These are Costa Rica, Georgia, Iran, and Mongolia.
People arriving into Ireland from these states, or transiting through them, after 4.00am on Tuesday May 4th must complete mandatory hotel quarantine.
Health Minister Stephen Donnelly said the decision to add to the list was approved at a Government meeting earlier this week.
This status is also being revoked, as and from Friday, for: Bonaire, Sint Eustatius and Saba, San Marino, Monaco, Wallis and Futuna Islands and Moldova.
Minister Donnelly said: "The Government continues to advise against all non-essential international travel at this time.
"Protecting public health remains the key priority of Government.
"The scenes we are witnessing in India are distressing and a devastating reminder to us all of the severe illness and death COVID-19 can cause.
"The Government will continue to act to protect the population from variants of concern and take decisions that reinforce Ireland's biosecurity."
India has seen a massive surge in coronavirus cases and deaths.
Ireland has donated 700 oxygen concentrators, personal protective equipment (PPE) and medical essentials to India as part of international efforts to help.
Minister Donnelly also said more supplies would be sent to India on Monday - including oxygen generators, concentrators and ventilators.
Amazing work from @roinnslainte @HSELive @DeptHousingIRL @dfatirl @Irish_Aid to get Oxygen Concentrators to Red Cross in India
Another consignment will leave on Monday - 2 oxygen generators, 548 oxygen concentrators, 365 ventilators and 60 mask ventilators pic.twitter.com/OitxyUNtbw
— Stephen Donnelly (@DonnellyStephen) April 30, 2021
While the World Health Organisation's Special Envoy on COVID-19, Dr David Nabarro, said what is happening in India could happen elsewhere.
"We are watching what's happening in so many other parts of the world.
"If you look at the current situation of numbers of cases occurring in different places - we're seeing upticks in numbers from the Middle East, from Latin America, and also from eastern Asia as well as south Asia.
"The basic message that I'm saying to everybody is what's happening in India could well happen in other places.
"What matters is everybody, everywhere needs to continue to apply the basic precautions that we've been talking about for the last few months," he said.
The full list of states is available here