Ministers will jet off to more than 30 destinations around the globe as part of St Patrick's Day celebrations.
The Taoiseach Micheál Martin will visit London and Washington DC, while Tánaiste Leo Varadkar will travel to Colombia and Chile
Transport Minister Eamon Ryan will visit New York as part of the programme.
Other destinations include the UAE, France, Canada, Lebanon, Romania, Japan, Poland and India.
While Foreign Affairs Minister Simon Coveney will stay at home for 'engagements on the island of Ireland' - as will Minister Heather Humphreys and Minister of State Malcolm Noonan.
This comes after in-person visits were only possible in a very limited way in 2020, and not at all in 2021.
The Government says the central message is that Ireland is re-opening, and the programme will focus on the theme of 'Rebuilding Connections'.
The 'Global Greening' will also continue this year - with over 600 landmarks around the world planned to be lit up green to celebrate St Patrick's Day.
Where in-person events are not possible, Irish diplomatic missions will host a series of online community, business and cultural events.
This will include country-specific 'virtual receptions' that will be broadcast on March 17th.
Here is the full list of ministerial destinations:
- Taoiseach London, UK; Washington D.C, USA
- Tánaiste Colombia; Chile
- Minister Ryan New York, USA
- Minister Donohoe The Netherlands; London, UK
- Minister McGrath San Francisco, USA; Vancouver, Canada
- Minister Martin Argentina
- Minister O’Brien UAE (Expo)
- Minister Coveney Minister on call/Engagements on island of Ireland
- Minister Foley Boston, USA
- Minister Humphreys No travel
- Minister O’Gorman New York, USA; Philadelphia, USA
- Minister Harris France
- Minister McEntee Savannah, USA
- Minister Donnelly Austin, USA
- Minister McConalogue Canada
- Minister of State Chambers L.A., USA
- Minister of State Hackett Greece
- Minister of State Naughton Australia; New Zealand
- Minister of State Byrne Italy
- Minister of State O’Donovan Chicago, USA
- Minister of State Smyth Spain; Portugal
- Minister of State Madigan Slovenia
- Minister of State Heydon Lebanon
- Minister of State Rabbitte Romania
- Minister of State Brophy Mexico
- Minister of State O’Brien Finland
- Minister of State Burke Japan; South Korea
- Minister of State Noonan No travel
- Minister of State Troy India
- Minister of State English Sweden
- Minister of State Butler Belgium
- Minister of State Feighan Poland
- Minister of State Collins Croatia
- Minister of State Fleming North of England; Scotland, UK
- Minister of State Browne Czech Republic
- Attorney General Washington D.C., USA