There have been a record 1,718 new cases of COVID-19 confirmed in the Republic, according to the Department of Health.
13 further deaths associated with the virus have also been reported in the past 24 hours.
The latest figures bring the total amount of cases here to 90,157, while the number of coronavirus-related deaths stands at 2,226.
Of the latest cases, 66% are under 45 years of age, while the median age is 34 years old.
Regarding the nationwide distribution of cases, 358 are in Dublin, 164 in Cork, 155 in Louth, 150 in Donegal, 112 in Galway and the remaining 779 cases are spread across all other counties.
853 are men and 863 are women.
As of 2pm today, 455 people are now receiving treatment in hospital for the virus after 60 new admissions in the past 24 hours.
Of those patients, 37 are in ICU, up three from yesterday.
The 14-day incidence rate per 100,000 of the population now stands at 272.7.
Dr Tony Holohan, Chief Medical Officer at the Department of Health said: "Ireland is no longer in a containment phase and is once again in a mitigation phase.
"Given the current levels of transmission in the community, every individual should consider themselves potentially infectious.
“It is essential that we all limit our contacts to our own household now, restrict our movements and do not give COVID-19 any further opportunities to spread.
He added: “Everyone needs to stay at home other than for essential work or care. This is not the time to be visiting other houses.”
Professor Philip Nolan, Chair of the NPHET Irish Epidemiological Modelling Advisory Group, said: “The reproduction number remains very high and is currently estimated at 1.6 – 1.8.
"The growth rate is estimated to be 7-10% per day with a doubling time of 7-10 days.
“We must take action immediately to prevent an almost unimaginable scenario, where case numbers in 7 to 10 days time are twice what they are today. Stay home.”
Meanwhile, a record 2,143 new cases of COVID-19 have been recorded in Northern Ireland in the last 24 hours.
There have also been six additional deaths reported by the Department of Health there.