There's so much we've yet to explore—from outer space to the deep ocean to our own brains. On this week's show, Manoush goes on a journey through those uncharted places, led by TED Science Curator David Biello.

Host Manoush Zomorodi and TED Science curator David Beillo begin their conversation by exploring the universe with TED speakers and astrophysicists Juna Kollmeier and Enrico Ramirez-Ruiz, whose work attempts to make sense of the vast and mysterious nature of space

Manoush and David dive into the furthest depths of the ocean with TED speaker Victor Vescovo, whose deep-sea submarine trips reveal lifeforms that defy imagination. Then, they end our episode about unexplored territory with neuroscientist Kay M. Tye, who describes an uncharted mystery closer to home: our own minds.