20 minutes after Simon Zebo was forced off with an injury, another one of Ireland's key men had to leave the action.
Jonathan Sexton had to be replaced by Ronan O'Gara after appearing to damage his hamstring in the 30th minute while kicking ahead on the right touchline.
The Leinster fly half had to be helped from the field as Ronan O'Gara came on to replace him with Ireland 6 - 0 down to two Owen Farrell penalties.
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©INPHO/Billy Stickland