Irish flanker Sean O'Brien has been ruled out of Ireland's clash with Australia later today.
Josh van der Flier will take his place in the starting line-up while Peter O'Mahony is named on the bench.
Breaking News: @SeanOBrien1987 ruled out. @joshvdf to start & @peterom6 on the bench. #TeamOfUs #shouldertoshoulder pic.twitter.com/Ab8189O4J7
— Irish Rugby (@IrishRugby) November 26, 2016
Rory Best leads the side in his 100th cap with Michael Cheika's Australia looking to ruin the party.
Elsewhere, England beat Argentina 27-14 despite playing the majority of the game with 14 men after Elliott Daly was sent off after a horrendous tackle on Leo Senatore. Late on Enriqure Pieretto, also saw red for stamping on Joe Marler's face.
It's full-time at Twickenham 🌹🌹🌹#CarryThemHome #ENGvARG pic.twitter.com/CVpnzkMFDW
— England Rugby (@EnglandRugby) November 26, 2016
Scotland beat Georgia 43-16 at Rugby Park in Kilmarnock while Italy followed up last weekend's historic win over South Africa by losing to Tonga 19-17.