Newcastle's first game in this season's Championship has ended in defeat.
Having been relegated from the Premier League last season, Rafael Benitez's side were beaten 1-0 at Fulham.
Matt Smith got the goal just before the break for the home team.
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Benitez has been reshaping the Newcastle squad this summer as they look for automatic promotion.
New signings Matt Ritchie, Grant Hanley and Marcus Gayle started the match.