Manu Tuilagi has been ruled out of England's rugby union tour of Australia this summer.
The Leicester player suffered a hamstring injury during his side's Premiership semi-final defeat to Saracens at the weekend.
The centre, who has been plagued by groin and hamstring injuries for two years, has suffered a grade-two hamstring tear, which he has suffered before and is an injury that tends to carry a six-week layoff.
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A replacement will be called up ahead of Sunday's game with Wales at Twickenham.