Leinster will be without James Ryan, Garry Ringrose and Will Connors for the Guinness PRO14 final meeting with Munster.
All three were absent from Ireland's Six Nations victory over England with respective head, ankle and knee injuries.
Leinster are due to face Munster in the PRO14's Grand Final at the RDS.
Ryan is continuing to follow the return-to-play protocols having picked up a second head injury of the Six Nations campaign in the win over Scotland.
Ringrose's ankle injury will keep the centre on the sideline - Leinster say - for "a number of weeks".
That almost certainly rules him out of their Heineken Champions Cup last-16 clash with Toulon, and the quarter-final away to either Exeter or Lyon should they progress.
But Connors' European campaign looks to be over.
The flanker suffered a knee injury during Ireland training ahead of the England game, costing him a starting place.
He'll be out for up to eight weeks as a result.
There is positive news for Leo Cullen and co ahead of Munster's arrival to the RDS. Luke McGrath has passed the Graduated Return to Play Protocols and is due to train this week.
Sean Cronin came through Friday's PRO14 defeat to the Ospreys unscathed.
And Vakh Abdaladze will also look to increase his involvement in team training this week as he continues to recover from a back injury.