England full-back Mike Brown will definitely miss Sunday's Six Nations match against Ireland in Dublin.
Both Joe Schmidt and Stuart Lancaster's sides are two-from-two going into the showdown which could prove to be a Championship decider.
No surprise to see Mike Brown is doubtful for Ireland-England. Amazing how many people downplayed his KO in the Italy game. Alarm bells rang
— Paul Hayward (@_PaulHayward) February 24, 2015
The Harlequins man suffered a setback in his recovery from concussion, which he incurred against Italy a week-and-a-half ago.
Brown has not been able to get past stage three of the return-to-play protocol.
Saracens' Andy Goode is likely to take his place.