The Taoiseach Leo Varadkar says from midnight tonight until April 12th, everybody must stay at home.
This is unless they must go to work which is essential and cannot be done from home.
People can also go outside to shop, to attend medical appointments, and for vital family reasons like caring for children and the elderly.
There were three more coronavirus deaths in Ireland on Friday.
The Health Protection Surveillance Centre (HPSC) says this was one person is in the north-west of the country and two women in the east.
There have now been 22 COVID-19 related deaths here.
Irish citizens in the US on certain visas are being advised to leave the country.
It comes after the number of coronavirus cases there jumped significantly.
The US became the country with the most cases in the world on Thursday.
The company that runs the USIT visa programme for students says it has appointed joint liquidators to it.
Kinlay Group Ltd says liquidators have also been appointed to the English Studio language school.
USIT specialises in international recruitment and work abroad programmes in the USA, Canada and Australia.
The UK Prime Minister Boris Johnson and Health Secretary Matt Hancock have both tested positive for COVID-19.
In a tweet, Mr Johnson said he had “developed mild symptoms” over the past few days and has now tested positive.
He said he is now working from home and self-isolating.