The Egyptian military has given President Morsi and his opponents 48 hours to meet the demands of the people - or it says it will step in.
The military alled the ultimatum "a final chance to shoulder the burden of a historic moment in our country."
Tens of thousands of protesters have gathered in Cairo again tonight - continuing to call for the president to resign.
The crowd, growing larger by the hour, cheered as military helicopters passed overhead, some of them trailing Egyptian flags.
Eight people have now died as activists stormed and ransacked the Cairo headquarters of the Muslim Brotherhood, to which the president belongs.
Its reported that the ministers of tourism, environment, communication and legal affairs have now resigned
US President Barack Obama has also called for restraint on all sides.