A healthcare firm is to create 140 jobs in Dublin.
The US$100m (€88.3m) ivestment by Grifols will be a first-ever life sciences investment by a Spanish company in Ireland.
The new facility in Grange Castle will centralise decision-making over commercial policy, R&D and the supply chain needs of its bioscience division - which specialises in plasma protein therapies.
The site will also house operating activities such as warehousing of plasma, intermediate paste and finished product; labeling, packaging, final conditioning; and administrative procedures.
It is scheduled to come on stream in the first half of next year.
Grifols says its bioscience sivision generated 75% of the group's total net revenue in 2014.
The company currently has a direct commercial presence in 30 countries, and distributes its products in 100.
The announcement was made by Jobs Minister Richard Bruton, Justice Minister Frances Fitzgerald, the Spanish High Commissioner for Marca España, Carlos Espinosa de los Monteros and the Spanish Ambassador to Ireland, José María Rodríguez-Coso.