The head of the Health Service Executive (HSE) says there have been over 40,000 applications for its 'On Call for Ireland' initiative.
The group has been asking all healthcare professionals from all disciplines, who are not already working in the public health service, to register.
"We will be creating extra hospital and care beds and will need extra hands to provide the care that’s needed", the HSE says.
"We need your help to meet the challenge that’s ahead."
In its description, the initiative adds: "Maybe you aren’t a healthcare professional, maybe you’re studying to be one, or maybe you have other skills to offer or just want to volunteer to do your bit if needed.
"Hopefully we won’t need to call, and if we do, we may not need every one of you. But knowing you are there if we do will make all the difference."
People can register their interest here - where they will be asked for details of experience or skills.
HSE chief Paul Reid has described the response as "overwhelming support from business, communities, social groups and individuals."
"We will shortly commence a really tough time but all of us in HSE are inspired by this response. Thank you all so much", he said.
Over 40K applications for "On Call for Ireland" in @HSELive Overwhelming support from business, communities, social groups, & individuals. We will shortly commence a really tough time but all of us in HSE are inspired by this response. Thank you all so much #COVID19
— Paul Reid (@paulreiddublin) March 19, 2020
It comes as a third person has died from the coronavirus here.
On Thursday there were 191 new confirmed cases of COVID-19 in Ireland - 557 in total.
Data from the Health Protection Surveillance Centre (HPSC), as of midnight on Tuesday, revealed that of the 350 cases 55% were men and 43% women, with 26 clusters.
The median age of confirmed cases is 43 years.
Some 31% of cases have been hospitalised, with 2% (seven cases) admitted to an ICU.
While 84 cases are associated with healthcare workers, 28 of whom are linked with foreign travel.
Dublin has the highest number of cases at 172, followed by Cork (62) and Limerick (14).
Dr Tony Holohan, chief medical officer in the Department of Health, said: “I would like to extend my condolences to the family and friends of this patient.
“It is too early to see any impact of our social distancing measures.
"This data underscores the importance of younger people to rigorously follow public health advice and social distancing measures."
