Childline has seen a 20% increase in the number of children contacting them since the coronavirus crisis began.
The ISPCC service has said it will continue to operate and listen to every child and young person in Ireland.
The service has appealed for public support to help ensure it can meet the increase in demand, at a time when vital fundraising activities must be curtailed.
Childline receives an average of 1,000 contacts every day from children and young people across Ireland.
ISPCC Cildline chief executive John Church said: "Imagine being a child at home right now, except their home is not a happy place.
"They are isolated from their regular support network and at home with their tormentor. Childline is a lifeline.
"Life as we know it has been put on hold for now – and so have the vital fundraising activities on which Childline depends for its continued existence.
"But child abuse does not stop in a pandemic, nor does neglect.
"Nor do mental health difficulties or self-harm."
He added: "In many cases, children and young people across the country are experiencing these issues more acutely now than ever before.
"Many of those who contact Childline tell us they feel as though they have nowhere else to turn - they need our help."
"Childline will continue to be there for them 24 hours a day, every day - but only if we receive public support at this critical time."
The service relies on donations for 90% of its funding.
People can donate online here
Anyone affected by issues raised in this article can contact Childline on 1800-66-66 66 or free text to 50101