SIPTU says a company creating 400 jobs in Dublin needs to say whether it's going to rehire some staff it's already laying off.
Pharmaceutical company Bristol Myers Squibb is creating the jobs at a new manufacturing plant at Cruiserath in north Dublin.
1,000 jobs will also be created during the construction phase at the biological medical company - expected to be completed in 2018.
However, the news comes only eight months after the company said it would be closing a separate plant on the same site, with 130 workers being let go.
SIPTU organiser Michelle Quinn wants more clarity on whether those jobs can be saved: