Manchester United v Shakhtar Donetsk
The out-of-form Reds have injury concerns surrounding Nemanja Vidic, Patrice Evra, Marouane Fellani and Chris Smalling who all missed training yesterday.
All four are doubts for tonight's clash. But Shinji Kagawa should be fit after having his stomach pumped following an alleged episode of "over-eating".
Robin Van Persie who returned to the starting line-up during Saturday's defeat to Newcastle is likely to partner Wayne Rooney up front.
Man United have already qualified for the knockout stages but need at least a draw to prevent Shakhtar Donetsk from topping the group.
Bayern Munich v Manchester City
The Sky Blues travel to Germany still smarting from the 3 - 1 hammering at the hands of the European champions.
Manuel Pellegrini's side were fortunate to escape the Etihad with a two-goal loss. But they do have a chance of overtaking Bayern in the Group D standings.
A win by three goals will allow City to go top and avoid the likes of Real Madrid and PSG in the next round.
David Silva returns to the squad after a month on the sidelines, but Yaya Toure is suspended and Gael Clichy is injured.
Joe Hart is likely to start in goal as Pellegrini may choose to rest players with Sunday's game against Arsenal in mind.
