A Shane Long brace for Southampton has restored the gap to Premier League leaders Chelsea to four points.
The brace came during a relatively low-scoring afternoon in the Premiership, where not a single goal was recorded in the first halves of the four three o'clock kick-offs.
The Saints were ultimately 2-0 winners at home to Leicester.
Juan Mata's deflected second half shot gave Manchester United a 1-0 win at home to Crystal Palace.
Burnley have finally got their first win of the season, with Ashley Barnes' second half strike giving the Clarets a 1-0 win at home to Hull.
West Ham and Aston Villa drew a blank at Upton Park.
Earlier, goals from Gary Cahill and Diego Costa gave Chelsea a 2-1 win at Liverpool.
The half-five kick-off will see QPR host a Manchester City side bruised by their Champions League defeat on Wednesday night.
Full-time scores
Liverpool 1 - 2 Chelsea
(L: Cam 9' ; C: Cahill 14', Costa 67')
Burnley 1 - 0 Hull
(B: Barnes 50')
Man United 1 - 0 Crystal Palace
(MU: Mata 67')
Southampton 2 - 0 Leicester City
(S: Long 75', 80')
West Ham 0 - 0 Aston Villa
