JJ Hanrahan takes over at out for half for Munsters clash with Glasgow tomorrow night at Scoutston stadium.
Andrew Conway , Ivan Dineen, Ronan O'Mahony also come into the back line while Johnee Murphy moves from wing to full back.
Connor Murray who's being linked with Racing Metro today starts at scrum half.
James Cronin , Mike Sherry and Stephen Archer come into an all changed front row while O'Connell and O'Callaghan stay in the second row while Peter O'Mahony, Sean Dougall and CJ Stander form the back row.
Munster: Johne Murphy; Andrew Conway, Keith Earls, Ivan Dineen, Ronan O'Mahony; JJ Hanrahan, Conor Murray; James Cronin, Mike Sherry, Stephen Archer; Donncha O'Callaghan, Paul O'Connell; Peter O'Mahony Capt., Sean Dougall, CJ Stander. Replacements: Damien Varley, Dave Kilcoyne, BJ Botha, Billy Holland, James Coughlan, Cathal Sheridan, James Downey, Casey Laulala.