Liverpool's reward for reaching the Capital One Cup quarter-final is an away trip to a Southampton side they drew 1-1 against at the weekend.
The Reds beat Bournemouth tonight, while Southampton saw off Aston Villa in tonight's quarter-final before both sides were pitted together in the draw.
Manchester City have been handed a home tie against Championship side Hull City, while Everton travel to Manchester United's conquerors Middlesbrough.
The fourth last-eight tie sees Stoke City welcoming Sheffield Wednesday to the Britannia Stadium after both sides defeated Chelsea and Arsenal respectively last night.