Interim Ireland boss Noel King has confirmed that Darron Gibson suffered a cruciate knee ligament injury during last nights 3-1 win over Kazakhstan at the Aviva.
The Derry man collapsed in a heap after coming off worse in a first half challenge.
The Everton midfielder is due to undergo a scan upon his return to Everton today but faces a lengthy lay-off.
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He could be out for months and may miss the rest of this season for club and country, depending on the time-scale.