The single vehicle incident happened on the Dunshaughlin to Dunboyne Road at approximately 12.30.
The driver of the car- a 21 year old man -was fatally injured when the car he was driving collided with a ditch. Five other people-including three males and two females- were in the car. Their injuries are described as not life threatening.
The road is closed to allow gardai to carry out a forensic examination and local diversions are in place.
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Anyone who witnessed the incident is asked to contact Dunshaughlin garda station.