Farmers are planning a "large scale protest" in Dublin city on Wednesday.
It part of their ongoing campaign over beef prices, carbon tax and other issues.
Gardaí say around 400 tractors are expected to converge on the city centre from the early afternoon.
Tractors will gather in Merrion Square at 2.00pm before making their way to Leinster House.
Traffic delays are expected on the main arterial routes into the city - such as the N2,N3,N4,N7 and N81 - from 12.00pm when the tractors start arriving.
Bus corridors are not expected to be impacted and Gardaí are advising commuters to use public transport where possible.
Gardaí say disruption will start from 10.00am when road closures will come into effect on:
- Kildare Street
- Molesworth Street
- St Stephen's Green South
- Merrion Square West/South/East
- Merrion Street Upper
There will also be some diversions in place, such as east bound traffic on Kevin Street - which will be diverted up New Bride Street.
While St Stephen's Green North and East will only be open to public transport from 2.00pm.
In November, the 'Individual Farmers of Ireland' organised for more than 300 tractors to descend on the capital to protest.
Last Thursday, a meeting of the Beef Taskforce saw supermarket retailers meet farming organisations to try to resolve the dispute.
But the 'Individual Farmers of Ireland' were unhappy with the progress made.
Gardaí say they are continuing to liaise closely with those organising the protest.