The Mater Hospital's old Accident and Emergency Department will close today with the opening of a new new state of the art facility tomorrow.
It follows years of vigils and campaigns by local people for an improvement in conditions there.
The Labour Party will hold a final vigil outside the Mater hospital A&E in Dublin this lunchtime.
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Trade and Development Minister Joe Costello said it's been a long hard grind getting to this point, but it's been worth it: