The local lockdown for Kildare has been extended for two weeks.
However, schools in the county will reopen as planned over the next 10 days.
The restrictions which have been in place for Laois and Offaly over the past fortnight have been lifted.
Acting Chief Medical Officer Dr Ronan Glynn thanked people in all three of the counties for their efforts since August 7th.
However, he said that "unfortunately" NPHET has decided that the COVID-19 situation in Kildare "differs considerably" from that observed in Laois and Offaly.
He said a high number of cases continue to be reported in the county on a daily basis, with cases "widely distributed" across the county.
Mr Glynn stressed there is cause for "cautious optimism", including limited evidence of community transmission.
Tánaiste Leo Varadkar says he realises the news for people in Co Kildare is 'disappointing', but has pledged the Government will provide further assistance to businesses in the county.
In a statement, Mr Varadkar said: "It has been a devastating few months for business owners, their staff and families. By extending these restrictions now, we will avoid further, more damaging measures later on.
"We must do everything we can to protect people. The people of Kildare are making a sacrifice on behalf of the entire country. I recognise that and we are redoubling our efforts to help businesses.”
A number of measures are set to be 'stepped up' - including a 20% top-up to the existing restart grant.