The Government has revealed details of a €28m economic stimulus package for the border region.
The package applies to counties Donegal, Sligo, Leitrim, Cavan, Monaghan and Louth.
It is designed to drive economic activity in the region and ensure that businesses have additional support in mitigating the impact of Brexit.
The package includes €3m for the six Local Enterprise Offices, an €8.5m Brexit Transformation Fund and €1.5m for Industry Fellowships - targeted at businesses located in border counties.
A €15m competitive Border Enterprise Development Fund, administered by Enterprise Ireland, will also be introduced.
Competitive Feasibility Funding is also available - this will be a grant of €15,000 or 50% of eligible costs, whichever is lesser.
Business Minister Heather Humphreys said: "All of the research shows that the border region is most exposed to the impact of Brexit.
"I want to ensure that businesses in the region are supported by Government in responding to the challenges and uncertainties which lie ahead.
"This is the first time my department has provided targeted, ringfenced funding to a specific region which represents a strong statement of our commitment to the border area.
"Through this package of measures, I want to make businesses in the border region more resilient, more innovative and more competitive so that we can stimulate enhanced economic activity in the region."
Minister Humphreys also announced three new advanced technology buildings will be built in Dundalk, Monaghan and Sligo in 2020.
These buildings, as part of the next phase of the IDA's Regional Property Programme, will be used to attract more foreign direct investment to the border region.
She added: "This is a golden opportunity for businesses in the border region and I want to ensure that they get the maximum benefit out of this funding.
"I would therefore encourage companies to attend these workshops, details of which will be announced shortly, so that they can hear directly from our enterprise agencies about what's involved."
Britain is set to leave the European Union by the revised deadline of January 31st.