The 6.1 quake comes just days after a devastating tremor left 295 people dead.
Another strong earthquake has hit Mexico - just days after a devastating tremor left 295 people dead.
The US Geological Survey said the 6.1 quake was centred about 11 miles (18km) south-southeast of Matias Romero in the southern state of Oaxaca.
Details on damage or injuries are not immediately clear.
Buildings swayed and a seismic alarm was set off in the capital, Mexico City, where rescuers have been trying to reach people who remain buried in rubble from Thursday's quake.
Those rescuers have been forced to suspend their efforts.
"I heard the alarm and ran downstairs with my family," said Sergio Cedillo, a resident who was watching rescue efforts when the alarm sounded.
Alejandra Castellanos, who was staying in a hotel in the area with her husband, said she was "frightened" when she felt the earth shake for the second time in two weeks.
"I was frightened because I thought, ‘not again,’" she said.
On the 7th September southern Mexico was hit by a huge magnitude 8.1 tremor.
That was followed by Thursday’s quake that took the lives of 295 people. The combined death toll from the two events is thought to be over 400.
The Central American country suffers so much because of its position on a large grid of tectonic plates.
It also sits on the 'Ring of Fire', a horseshoe shaped area around the edges of the Pacific Ocean, from Australia to the Andes, along which 90% of all earthquakes occur.