The alert is in place from Saturday night
Met Éireann has extended an orange weather warning for snow and ice.
The alert is in place from Saturday night for Connacht, Cavan, Monaghan, Donegal, Dublin, Kildare, Laois, Longford, Louth, Wicklow, Offaly, Westmeath and Meath.
The forecaster says "significant" snowfall is expected Saturday night and into Sunday.
Accumulations of between 4 to 8 cms could occur widely, with greater totals possible.
There will also be drifting snow locally at times too, as well as brisk winds.
It is warning that there will be slippery footpaths and "treacherous" road conditions as a result.
It comes after two other snow and ice warnings were issued on Thursday.