Protesters shouted, "not my President" and held placards urging the public to "fight racism."
Thousands have taken to the streets across America in protest at Donald Trump's surprise victory in the presidential election.
Demonstrators descended on midtown Manhattan and advanced towards the President-elect's home - Trump Tower - angered by his campaign rhetoric on Muslims and immigration.
Protesters shouted, "not my President" and expressed concern about America’s new reality, with placards urging the public to "fight racism."
In Oakland, California, rioting protesters smashed shop-front windows and threw objects at police in riot gear - who responded by throwing chemical irritants back at the crowds.
Police in Chicago set up blockades to stop approximately 1,800 protesters gathering outside the Trump International Hotel.
In his victory speech yesterday morning, Trump said he aims to be a president for all Americans, adding: "It is time for us to come together as one united people."
The president-elect has yet to respond to the protests.
As the shockwaves of his surprise win continue to be felt around the world, it has emerged the next American president has wasted no time in speaking to the leaders of several countries closely tied to US foreign policy.
Trump held discussions with South Korean president Park Geun-Hye and Australian premier Malcolm Turnbull while Japanese officials confirmed the importance of the Japan-US alliance and US commitment to cooperation.
He is expected to have a phone conversation with British Prime Minister Theresa May "at the earliest opportunity" after she congratulated him on his victory on Wednesday.
Mexican President Enrique Pena Nieto has also said he plans to meet Trump during the transition period following a "cordial, friendly and respectful conversation" in the wake of his win.
Later today, the President-elect will meet Barack Obama in the White House, where they will discuss January's handover of power.
Their talks in the Oval Office are scheduled to begin at 4pm Irish time, as First Lady Michelle Obama hosts Melania Trump in the residence.
Security has already been ramped up for the President-elect, with air space restrictions imposed over Trump Tower in New York City. Rubbish trucks filled with earth have also been parked outside the entrance to the high-rise building, forming a protective barrier.
Inside, Trump and his senior aides are plotting their next steps - with a campaign source telling Reuters that they have been hunkered down in meetings to plan the administration's first 100 days - and decide who should serve in key staff positions.
Among those tipped for senior posts are former New York mayor Rudy Giuliani and New Jersey governor Chris Christie, Both of whom eagerly supported Trump during the race.
The White House has begun to make the President's daily briefing and other intelligence files available to Trump and Vice President-elect Mike Pence, a courtesy that George W Bush extended to Barack Obama as he was preparing to take office.