Two medical staff were also injured in the strikes
Two medical facilities in the besieged Syrian city of Aleppo have been bombed.
Médecins Sans Frontières (MSF) say the two hospitals in the east of the city cover 250,000 people.
The medical charity say the buildings were severely damaged in Tuesday night's "indiscriminate bombing" of the city.
It says they have been forced to halt all activities.
The two attacks caused the death of at least two patients and injured two medical staff.
MSF say only two other medical facilities with surgical capacity are left in this area.
"According to different medical sources, there are only seven surgical doctors left in the area, serving an estimated population of 250 000", says Carlos Francisco, MSF's head of mission for Syria.
"And this comes at a time when east Aleppo has been under siege since July and is suffering the bloodiest indiscriminate bombing since the beginning of the war. We don’t know how to say it anymore: This has to stop."
The attack coincides with a planned work strike by non-emergency doctors, medical staff and humanitarians for three hours to protest against the continued targeting of medical facilities and health professionals.
MSF supports eight hospitals in Aleppo city.
It runs six medical facilities across northern Syria and supports more than 150 health centres and hospitals across the country, many of them in besieged areas.
The UN Special Envoy for Syria, Staffan de Mistura, said airstrikes are reported to have killed 213 people in Aleppo province over the weekend.
Information received by Office of the UN High Commissioner for Human Rights (OHCHR) indicates dozens of airstrikes on Friday and Saturday hit residential buildings, causing scores of reported civilian deaths and injuries - including many children.