Failure can feel lonely and final. But can we learn from failure, even reframe it, to feel more like a temporary setback? On this week's show, TED speakers on changing a crushing defeat into a stepping stone.

After her business failed, Leticia Gasca didn't talk about it for seven years. But once she finally shared the story with her friends, she realized failure is far more common than she thought.

Why do we fixate on the negative? Why do setbacks stick in our minds for so long? Alison Ledgerwood shares ideas on how we can change our thinking patterns to reframe setbacks in a positive light.

When it comes to scientific research, mistakes are not only part of -- but crucial -- to the process. Phil Plait explains how small setbacks can play a critical role in making big discoveries.

As a former pro runner, Charly Haversat would fixate on an unattainable goal: perfection. She discusses the crippling effects of perfectionism, including how it can prevent learning from failure.

Everyone makes mistakes, but sometimes mistakes have big consequences. Jon Bowers argues that we should always strive for perfection -- knowing we will fail and we have to learn from those failures