The United Nations is calling on all sides in the Syria city of Aleppo to reach a truce.
It says more than two million people have been impacted by the fighting in and around the war-ravaged city.
"Swaths of the area are now without power and water supplies are dwindling", the UN says in a statement.
It has urgently called for a humanitarian pause in hostilities "to enable immediate access to repair the electricity and water networks, and provide assistance to people in need."
Yacoub El Hillo, UN resident and humanitarian coordinator for Syria, and Kevin Kennedy, regional humanitarian coordinator for the Syria Crisis, also noted that over the past few weeks communities in both east and west Aleppo have borne the brunt of the conflict, with countless civilians dead or injured.
"The targeting of hospitals and clinics continues unabated, seriously jeopardizing the health and welfare of all citizens of Aleppo," El Hillo and Kennedy said.
They say that water available through wells and tanks in Aleppo is not nearly enough to sustain the needs of the population.
'Full-fledged ceasefire'
"The UN is extremely concerned that the consequences will be dire for millions of civilians if the electricity and water networks are not immediately repaired," they said.
"The UN stands ready to assist the civilian population of Aleppo, a city now united in its suffering. At a minimum, the UN requires a full-fledged ceasefire or weekly 48-hour humanitarian pauses to reach the millions of people in need throughout Aleppo and replenish the food and medicine stocks, which are running dangerously low."
"The UN reiterates its call for the immediate lifting of all sieges. When used to intentionally deprive people of food and other items essential to their survival, siege tactics constitute a war crime," they added.
According to the UN Office for the Coordination of Humanitarian Affairs (OCHA), an estimated 250,000 to 275,000 people have remained trapped in east Aleppo since early July following the closure of Castello Road - the last remaining access route into the area.
Since August 6th, Khanasser Road - the main access route into west Aleppo - has also been cut.
This brings the total number of civilians living in "de facto fear of besiegement" to over two million, it adds.
