Five people, including three young children, have died in a house fire in Sheffield despite heroic efforts to save the youngsters.

Two women are believed to have died alongside the children after a blaze in Wake Road, Sharrow, shortly after midnight.

Neighbours said they believed the victims included a baby girl, two boys and their aunt and grandmother.

One neighbour told how they saw the grandmother run screaming from the blazing home, before going back inside to try and save the young victims.

A South Yorkshire Fire and Rescue spokesman said the cause of the blaze was being investigated.

Scenes of crime officers have sealed off the road, erected a tent outside the three-storey terraced home and are searching for clues.

A police spokesman said: "At this stage we are not able to confirm where in the house the fire broke out or if anyone else was injured."