The Government is to spend almost €1m to promote inclusion, protect rights and improve the quality of life and wellbeing of LGBTI+ people.
The National LGBTI+ Inclusion Strategy will run from 2019 to 2021.
It contains over 100 actions to support equality and LGBTI+ initiatives, and is underpinned by public consultations.
The Government says it reflects a commitment to create "an equal, fair and inclusive society for all, target discrimination and enable LGBTI+ people to overcome the barriers they face."
One of the key features is cross-departmental implementation, which will require action by the responsible departments.
The work will include reviewing implementation and agreeing key indicators for monitoring progress.
A committee will also assess whether or not further action is needed on specific issues, and making recommendations on actions to be added or changed.
The strategy is made up of four pillars; Visible and Included, Treated Equally, Healthy and Safe and Supported.
These will identify key large-scale events each year to promote LGBTI+ visibility, and explore opportunities for appropriate inclusion of LGBTI+ lives in the curriculum as part of a review at both primary and senior-cycle levels.
A civil and public service-wide employee and ally network is also to be set up.
Outstanding sections of the Adoption (Amendment) Act 2017, relating to donor-conceived children, will also be part of the strategy.
The committee will make a report to each House of the Oireachtas of the findings on the review of the Gender Recognition Act 2015 - and of the conclusions drawn from them.
In terms of health, sexual health programmes and campaigns will target at-risk groups.
While legislative proposals will also be brought forward under the strategy, to ensure that incitement to hatred and hate crimes against LGBTI+ people are "adequately addressed in our laws".
Justice Minister Charlie Flanagan secured additional funding of €700,000 for 2020, bringing the total funding available to over €900,000.
Speaking at the launch, Mr Flanagan said: "This is a national strategy because it speaks to Ireland - to the society we are, and the society we aspire to be.
"It is of the utmost importance that the strategy clearly responds to key issues facing the LGBTI+ community.
"I want to set an ambitious vision for Ireland, where the end goal is full equality for LGBTI+ people.