Ireland and Scotland are to hold a joint review, to look at how the two countries will cooperate and grow together over the next five years.
This is the first joint review undertaken by either country.
It will cover collaboration in key policy areas including trade, research and culture - as well as joint initiatives such as the Irish-Scottish Health Forum.
It will also focus on cooperation beyond government in the areas of business and economy, community and Diaspora.
The review will examine academic and research links, culture, and rural, coastal and island communities as part of its remit.
It will be led by the Consulate-General of Ireland in Edinburgh and the Scottish Government Hub in Dublin.
It will feature an online questionnaire and other public consultations - a joint report will then be published in the spring of 2020.
This report will set out shared goals and priorities for up to 2025.
This work is being supported by a steering group of Irish and Scottish officials to ensure that it remains focused and delivers on time.
People who feel they can contribute should get in touch with the Consulate General of Ireland in Edinburgh or the Scottish Government Hub in Dublin.
More information on the review can be found here.
Speaking on Monday, Tánaiste Simon Coveney said: "The age-old Ireland-Scotland relationship has developed and deepened over the last two decades - facilitated by devolution in the UK; the Good Friday Agreement and the establishment of the British-Irish Council; and the opening of our Consulate in Edinburgh.
"I am ambitious for the relationship, and want to build on existing excellent cooperation, and identify new shared policy areas where we can learn from each other, and collaborate for the benefit of our citizens.
"I urge all who care about the Ireland-Scotland relationship to engage fully with this review, which will bring new focus and energy to the collaboration between our governments in the years to come."
The external affairs secretary with the Scottish government, Fiona Hyslop, said: "Ireland is one of Scotland's oldest friends, linked by history, geography and culture.
"In this era of global uncertainty it is more important than ever that we seek to strengthen our relations even further, allowing us to improve in areas where we already work together and identify new opportunities for collaboration.
"I would invite those from Ireland and Scotland alike to take part in this review, so that our nations can face the future together from a position of strengthened collaboration and friendship."
It comes as Scottish First Minister Nicola Sturgeon has said she wants to hold a second independence referendum from the UK by May 2021.
Voters in Scotland chose to remain a part of the United Kingdom in a 2014 referendum - but Ms Sturgeon said in April that the 2016 vote for Brexit, which saw Scotland vote in favour of remain, had changed things.
She told Scottish MPs that the case for independence was now "stronger than ever".