340 new jobs have been announced in Cork, Dublin and Limerick.
140 positions are being created at GE Healthcare in Cork.
The company plans to double existing production capacity at its Carrigtwohill operation.
It makes medical imaging contrast media and already employs 500 people in East Cork.
Meanwhile, 100 new full time jobs have been announced with the expansion of the Limerick Institute of Technology.
134 more jobs will be offered during the construction phase.
Limerick IT is developing a new campus at Coonagh Cross for engineering and pharmacy students.
The project will receive €3.5 million in government funding and the first intake of students is scheduled for next year.
Elsewhere, 100 new positions are being created at digital communications company, Neopost in Citywest in Dublin.
And 100 new jobs are being created at a new engineering and pharmacy campus at the Limerick Institute of Technology.
