The national association of charities has called for donations from the public and companies amid the COVID-19 crisis.
The Wheel, which represents over 1,700 charities, community and voluntary organisations across Ireland, issued the plea for urgent funds to maintain key health services and supports.
The organisation has asked for donations to charities that are working on the front line to support and protect vulnerable people in communities during the pandemic.
It said that a combination of surging demand and the collapse of normal fundraising income means that charities need public support immediately.
In a statement, the association said that the Irish Cancer Society is down a projected €4m after the cancellation of Daffodil Day while Pieta House is down up to €6m due to the postponement of the Darkness to Light fundraiser.
The Wheel also said that many local charities and community groups will receive decreased funding due to the suspension of church gate collections.
Many charities will also see increased pressure on their services as people seek support following redundancies as a result of COVID-19.
Deirdre Garvey, CEO of The Wheel, said: “Tens of thousands of people woke up this morning with their jobs and income at risk.
"Our charities and community groups will be facing unprecedented demands to support people in these distressing times.
"The many others who are lucky to have secure employment and income have an important opportunity to support others by donating to organisations providing services in health and disability, meals on wheels, homelessness, carer supports, poverty relief and other crucial services.
“Making donations, however big or small, to the many charities that are working to preserve health and social services, and maintain the very fabric of our society at this time, is something that should be expected of those who can afford it.
She added that the organisation would also be calling on the government to implement a plan to support the work of charities.