Prison Break star Wentworth Miller took to Facebook to reveal his battle with depression as he criticised a meme that sought to poke fun at his appearance in a 2010 photograph. 

The 43-year-old posted a screenshot of the meme, which has now been deleted by the original poster, The Lad Bible, on his Facebook page and opened up about his battle with depression and eating.

“Today I found myself the subject of an Internet meme. Not for the first time. This one, however, stands out from the rest,” Wentworth wrote on his Facebook page.

"In 2010, semi-retired from acting, I was keeping a low-profile for a number of reasons. First and foremost, I was suicidal," he wrote.

"This is a subject I've since written about, spoken about, shared about. But at the time I suffered in silence. As so many do. The extent of my struggle known to very, very few.

"Ashamed and in pain, I considered myself damaged goods. And the voices in my head urged me down the path to self-destruction. Not for the first time. I've struggled with depression since childhood. It's a battle that's cost me time, opportunities, relationships, and a thousand sleepless nights." 

The actor revealed that he turned to food in his troubles, which he says, was "the one thing I could look forward to" and "count on" to get through. 

"There were stretches when the highlight of my week was a favorite meal and a new episode of TOP CHEF. Sometimes that was enough. Had to be," he wrote. "And I put on weight. Big f—king deal."  

Miller recalls first seeing the image and negative comments about his weight gain back in 2010 and the dent he took to his self esteem.

But, he was quick to point out that he has moved on and goes on to say, "Long story short, I survived.

"Now, when I see that image of me in my red T-shirt, a rare smile on my face, I am reminded of my struggle. My endurance and my perseverance in the face of all kinds of demons. Some within. Some without," he said.

The actor ends the lengthy post with some advice for anyone in a similar situation: "If you or someone you know is struggling, help is available. Reach out. Text. Send an email. Pick up the phone. Someone cares. They're waiting to hear from you." 

The LadBible, which markets itself as a website for males aged 16-30, has since removed the meme and apologised for the “pain” caused by the post.

“We posted two pictures of you last night to our Facebook page, but today we want to say we’ve got this very, very wrong. Mental health is no joke or laughing matter,” read a statement on their website.

“We certainly didn’t want to cause you pain by reminding you of such a low point in your life. Causing distress and upset to innocent or vulnerable people is simply not acceptable.

“TheLADbible continues to cover how prevalent mental health issues are among our audience, as well as the damaging stigma that surrounds such matters.

“We applaud your raw honesty and promise to now cover such matters in the responsible manner that our audience expects.

“Responding head-on to our post is something we applaud as it will help others through similar challenges in their lives.

“Once again, we got this very wrong, and we wanted to say sorry,” the statement concluded.