It follows a row over available funding
The Health Service Executive (HSE) says it has recommended nine new high-tech treatments for approval.
This follows discussions between the Department of Health and HSE over funding.
The drugs include those used to treat cancer, heart disease and depression.
The HSE says it received a letter from the Department of Health on Friday, in which "clarification has been provided".
This clarity was in relation to sustainable funding arrangements for these nine treatments for 2018 and beyond.
The HSE says it will now commence the "prescribing process and protocols" that would apply to any new drug for these treatments.
It will also begin the process of funding the treatments this year.
In a statement, the HSE says: "The process will be expedited, completed as soon as is feasibly possible and some of the treatments available towards the end of September 2017.
"While speedy provision of these nine treatments is a priority, of paramount concern is patient safety."
The HSE says it will fund these treatments from its existing resources.
Health Minister Simon Harris has welcomed the decision: "This represents another major investment by the HSE in innovative medicines.
"The decision by the HSE on each treatment is very significant and important for the patients involved."
Minister Harris had asked that the issue be resolved as a matter of urgency, so that patients were not adversely affected.
He added: "The speedy provision of these nine treatments is a priority, and I expect the HSE to conclude all the necessary processes - clinical, commercial and legal - as a matter of priority, to ensure that clinicians and patients have access to these treatment options as soon as possible."