A 42-year-old woman has been arrested following the incident
Police say the incident is not believed to be terror related and they are still trying to establish exactly what happened.
WESTGATE SPORTS CENTRE UPDATE: It is now confirmed that their are six casualties.— Northumbria Police (@northumbriapol) June 25, 2017
Six people have been taken to the Royal Victoria Infirmary, including three children. Two children are in intensive care after the incident.
North East Ambulance Service say the air ambulance is at the scene along with six ambulances and rapid response paramedics.
A Northumbria Police spokesman said: "On Sunday June 25, at approximately 9.14am, Northumbria Police received reports that a vehicle had collided with pedestrians outside of Westgate Sports Centre, Newcastle upon Tyne.
"Police inquiries are ongoing to establish exactly what happened but, at this time, it is not believed to be a terror incident.
"Emergency services are currently at the scene and five casualties have been confirmed.
"Police have arrested a 42-year-old woman who is currently in police custody."
A full investigation into the collision has begun but a spokesman said police were not looking for any other suspects.
Newcastle City councillor Dipu Ahad, who went to the scene, said people were distraught and in tears amid fears of a terror attack.
He said: "But it became clear this was a freak accident, accidents do happen. Hopefully there will be no fatalities and we as a community pray for those who were hurt in the incident."
Extra officers are on patrol to reassure the public but police repeated that there is nothing to suggest the incident was terror-related.