Professor Luke O’Neill dives into the science behind Type-1 Diabetes for this week's podcast, answering a question from listener Sarah. Luke explains the key differences between Type-1 and other forms of diabetes, guiding us through the early symptoms—intense thirst, frequent urination, unexplained weight loss, fatigue, vision issues, and nausea—and highlighting the serious long-term complications, from kidney damage to blindness and ulcers.

Luke also breaks down how Type-1 Diabetes isn’t purely genetic, exploring the role of psychological stress alongside hereditary factors. He takes listeners through the latest treatments, from insulin therapy and lifestyle adjustments to cutting-edge innovations like insulin pumps and artificial pancreases.

The discussion moves into the exciting frontiers of research, including stem cell treatments targeting the pancreas, and Luke’s optimism that breakthroughs in Type-1 Diabetes could pave the way for tackling other autoimmune conditions. For anyone living with or curious about the disease, Luke’s insight offers both clarity and hope.

Listeners can request future topics by emailing laoneill@tcd.ie.