In the course of Luke's career he has explored many areas and asked many questions, but one illness and the mysteries around it has taken up more of his life than almost any other - rheumatoid arthritis. This week he gives us a whistle stop tour through the science of a subject close to his heart, and explains why after decades of work there are today some potentially groundbreaking developments in motion.

Listen and subscribe to Show Me the Science on Apple Podcasts and Spotify.

Download, listen and subscribe on the Newstalk App.

You can also listen to Newstalk live on newstalk.com or on Alexa, by adding the Newstalk skill and asking: 'Alexa, play Newstalk'.