SIPTU members in Trinity College Dublin (TCD) have voted for strike action.
The union says the dispute is over management's failure to offer permanent contracts to staff.
SIPTU's John King says they'll meet on Wednesday March 22nd to discuss their next step.
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"We would have close to 500 members right across Trinity College, and what we're seeing is that when staff are being recruited to replace staff who have left, they're invariably being recruited on precarious forms of non-permanent contracts of employment."