They finish the tournament in Twickenham on St. Partick's Day
Ireland will open their 2018 Six Nations campaign in Paris against France on the first weekend in February.
Joe Schmidt's men then have three home matches in a row against Italy, Wales and Scotland before heading to Twickenham to take on current champions England on St. Patrick's Day.
The Six Nations organising committee have also released the schedule for the 2019 tournament where Ireland welcome England to the Aviva Stadium on the opening weekend.
The 2014 and 2015 winners then have back-to-back away games against Scotland and Italy before welcoming France to Dublin.
A general view of the Principality Stadium. Image: ©INPHO/Billy Stickland
The men in green finish the tournament away to Wales in Cardiff.