Munster are two points off the top of the table
Munster's Director of Rugby Rassie Erasmus has made nine changes to the team that beat Glasgow last weekend.
Dave Kilcoyne, Niall Scannell and John Ryan have been named in the front row with Donnacha Ryan and Billy Holland starting in the second row.
Jack O'Donoghue starts at number eight with captain Peter O'Mahony and Tommy O'Donnell on the flanks.
Duncan Williams and Tyler Bleyendaal are the half back pairing with Rory Scannell partnering Francis Saili in the centre.
Keith Earls and Darren Sweetnam start on the wings with Simon Zebo at full back.
Rhys Marshall, James Cronin, Stephen Archer, Dave O'Callaghan, Jean Deysel, Angus Lloyd, Ian Keatley and Andrew Conway are all named on the bench.
15. Simon Zebo
14. Darren Sweetnam
12 Rory Scannell
11. Keith Earls
10. Tyler Bleyendaal
9. Duncan Williams
1. Dave Kiloyne
2. Niall Scannell
3. John Ryan
4. Donnacha Ryan
5. Billy Holland
6. Peter O'Mahony (c)
7. Tommy O'Donnell
8. Jack O'Donoghue