Jared Payne, Kieran Marmion and Iain Henderson all start
Joe Schmidt has made three changes to his starting line-up for Ireland's final Six Nations game against England.
Jared Payne replaces the injured Rob Kearney at full-back, while Keiran Marmion starts at scrum-half instead of Conor Murray, who is also ruled out through an injury he suffered against Wales last weekend.
Meanwhile, Iain Henderson takes Devin Toner's place in the second row.
It's as you were in the front row with Jack McGrath and Tadgh Furlong packing down either side of captain Rory Best.
Donnacha Ryan partners Henderson at lock while the back-row of CJ Stander, Sean O'Brien and Jamie Heaslip remain unchanged.
Johnny Sexton continues at out-half with Robbie Henshaw and Garry Ringrose completing the midfield.
Simon Zebo and Keith Earls start on the wings with Payne completing the back three.
Niall Scannell, Cian Healy, John Ryan, Devin Toner, Peter O'Mahony, Luke McGrath, Paddy Jackson and Andrew Conway are named on the bench.
While silverware is off the table for Ireland this weekend, they will be playing for pride on home soil, as they look to prevent England from winning back-to-back Grand Slam victories in what would be a record 19th consecutive win.
Eddie Jones made two changes to his side for the Six Nations finale earlier today. Billy Vunipola is named to start at number 8, while Anthony Watson comes in to replace Jack Nowel.